Weaver was last seen about 08:30 a.m. on February 23, 1976.
Her husband was apparently supposed to meet her at their apartment around lunchtime that day to go look at a house. But when he got home, Weaver wasn't there.
Police say that foul play may be involved in her disappearance, but don't have any strong physical evidence pointing toward that. There is also no evidence to indicate that Weaver was experiencing any personal strife that might have prompted her to leave home willingly.
Her family said that she never had a history of leaving home, and none of her personal belongings, including her purse and her vehicle, were missing. (Information retrieved from NamUs.gov)